منابع مشابه
Cognitive maps beyond the hippocampus.
We present a conceptual framework for the role of the hippocampus and its afferent and efferent structures in rodent navigation. Our proposal is compatible with the behavioral, neurophysiological, anatomical, and neuropharmacological literature, and suggests a number of practical experiments that could support or refute it. We begin with a review of place cells and how the place code for an env...
متن کاملOverexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis.
Endogenous adenosine in the brain is thought to prevent the development and spread of seizures via a tonic anticonvulsant effect. Brain levels of adenosine are primarily regulated by the activity of adenosine kinase. To establish a link between adenosine kinase expression and seizure activity, we analyzed the expression of adenosine kinase in the brain of control mice and in a kainic acid-induc...
متن کاملCortisol and brain: beyond the hippocampus.
To the Editor: C arrion et al. (1) reported a negative association between bedtime cortisol level and left ventral prefrontal cortex volume in a group of 33 children and adolescents. Correlations id not differ between their posttraumatic stress symptom subroup and their healthy comparison subgroup. They concluded hat cortisol secretion may have an impact on prefrontal cortex evelopment and that...
متن کاملTheta phase precession beyond the hippocampus.
The spike timing of spatially tuned cells throughout the rodent hippocampal formation displays a strikingly robust and precise organization. In individual place cells, spikes precess relative to the theta local field potential (6-10 Hz) as an animal traverses a place field. At the population level, theta cycles shape repeated, compressed place cell sequences that correspond to coherent paths. T...
متن کاملExtracellular glutamate exposure facilitates group I mGluR-mediated epileptogenesis in the hippocampus.
Stimulation of group I mGluRs elicits several forms of translation-dependent neuronal plasticity including epileptogenesis. The translation process underlying plasticity induction is controlled by repressors including the fragile X mental retardation protein (FMRP). In the absence of FMRP-mediated repression, a condition that occurs in a mouse model (Fmr1(-/-)) of fragile X syndrome, group I mG...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2003
ISSN: 1535-7597,1535-7511
DOI: 10.1046/j.1535-7597.2003.03212.x